Disseminated disease refers to a diffuse disease -process, generally either infectious or neoplastic. To the Editor: Disseminated bacillus Calmette-Guérin (BCG) infection has been noted in patients with primary immunodeficiency. Disseminated intravascular coagulation (DIC) is a rare, life-threatening condition. As clotting factors and platelets are used up, bleeding may occur. Spontaneous bleeding may occur. Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! to spread or give out something, especially news, information, ideas, etc., to a lot of people: One of the organization's aims is to disseminate information about the disease. disseminated intravascular coagulation (DIC) a bleeding disorder characterized by abnormal reduction in the elements involved in blood clotting due to their use in widespread intravascular clotting. Multiple Sclerosis Definition Multiple sclerosis (MS) is a chronic autoimmune disorder affecting movement, ensation, and bodily functions. Disseminated disease has two main clinical presentations (overlap does occur) Chronic adult form: pulmonary and extrapulmonary (mucocutaneous often) involvement Acute to subacute juvenile form: reticuloendothelial system involvement (liver, spleen, lymph nodes); pulmonary complaints are minimal Immun⦠A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to "seed" other areas of the body. We report a case of a 60-year-old woman whose initial complaints of an erythematous, âburningâ rash and flu-like symptoms led to several laboratory tests with no ⦠A disseminated infection is one in which a localized infection spreads (disseminates) from one area of the body to other organ systems. Learn how and when to remove this template message, https://en.wikipedia.org/w/index.php?title=Disseminated_disease&oldid=951255225, Creative Commons Attribution-ShareAlike License, This page was last edited on 16 April 2020, at 07:43. Disseminate definition, to scatter or spread widely, as though sowing seed; promulgate extensively; broadcast; disperse: to disseminate information about preventive medicine. This generally occurs only in people with compromised or suppressed immune systems. A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to âseedâ other areas of the body. Disseminated definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Often affecting individuals with compromised immunity, it occurs when the virus spreads throughout the body. Can you spell these 10 commonly misspelled words? What made you want to look up disseminated? Thrombi may lead to vascular obstruction/ischemia and multiorgan failure. The fungus is known to live in the soil in the southwestern United States and parts of Mexico and Central and South America. It is often triggered by a viral infection or (very rarely) specific non-routine The rash does not usually cross the bodyâs midline. Histoplasmosis is most commonly transmitted when these spores become airborne, often during cleanup or demolition projects.Soil contaminated by bird or bat droppings also can transmit histoplasmosis, so farmers and landscapers are at a higher risk of contracting the disease. Medical Definition of disseminated. 'All Intensive Purposes' or 'All Intents and Purposes'? Disseminated disease is often contrasted with localized disease. The term may sometimes also characterize connective tissue disease. Cutaneous manifestations of malignant lung disease Apart from skin metastases and infections of the skin secondary to impaired host defence consequent upon disseminated cancer, there are several skin conditions that, although not malignant themselves, are sometimes associated with systemic cancer, including bronchopulmonary carcinoma. The rash most commonly appears on the trunk along a thoracic dermatome. Sometimes necessitating hospitalization, treatment for disseminated herpes zoster involves the administration of medications, including steroidal and antiviral drugs, to ease symptoms and prevent complications. DISH can also affect your neck and lower back, and some people have DISH in other areas, such as shoulders, elbows, knees and heels.DISH can be progressive. As it w⦠This condition is called disseminated zoster. You donât give it a second thought. This is localized infection. Disseminated Herpes Zoster. In rare situations, a brain biopsy may be necessary to differentiate between ADEM and some other diseases that involve inflammation and damage to myelin. Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. More from Merriam-Webster on disseminated, Thesaurus: All synonyms and antonyms for disseminated, Nglish: Translation of disseminated for Spanish Speakers, Britannica English: Translation of disseminated for Arabic Speakers. Disseminated herpes zoster is a complication of the herpes zoster virus. There are generally two types that are common in humans â those ⦠Acute disseminated encephalomyelitis (ADEM), or acute demyelinating encephalomyelitis, is a rare autoimmune disease marked by a sudden, widespread attack of inflammation in the brain and spinal cord. Which word describes a musical performance marked by the absence of instrumental accompaniment. Disseminated zoster ca⦠Disseminated intravascular coagulation (DIC) is a blood clotting disorder. This article summarizes our understanding of the pathophysiologic mechanisms that lead to disseminated MAC disease. Learn a new word every day. Histoplasmosis is an infection caused by breathing in spores of a fungus often found in bird and bat droppings. The timely diagnosis of early disseminated Lyme disease presenting as multiple secondary erythema migrans lesions is sometimes delayed because this stage is infrequently encountered in a general practice. A disseminated disease is a type of disease that has spread from its initial point of origin or contact in the body to other regions that were not its specific target of attack. Early disseminated Lyme disease is the phase of Lyme disease in which the bacteria that cause this condition have spread throughout your body. However, while many persons are transiently colonized with MAC, disease due to MAC is rare. noun a chronic progressive disease of the central nervous system characterized by loss of some of the myelin sheath surrounding certain nerve fibres and resulting in speech and visual disorders, tremor, muscular incoordination, partial ⦠'Nip it in the butt' or 'Nip it in the bud'? [4] We describe a case of dissemin ⦠Varicella-zoster is the virus that causes varicella (chicken pox), herpes zoster (shingles), and rarely, severe disseminated disease including diffuse rash, encephalitis, hepatitis, and pneumonitis. â Robert R. Redfield et al., Scientific American, October 1988 â see acute disseminated ⦠See more. Similarly, one can view metastatic cancer as a disseminated infection in that it has extended into the bloodstream or into the lymphatic system and thus "seeded" distant sites (a process known as metastasis). Usually, it propagates through the blood supply or lymph system that carries white blood cells in plasma to fight infections. “Disseminated.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/disseminated. In the early stages of the condition, DIC causes your blood ⦠Delivered to your inbox! Acute disseminated encephalomyelitis (ADEM) is a rare kind of inflammation that affects the brain and spinal cord, usually in children. Disseminated disease refers to a widespread or diffuse disease-process, generally either infectious or neoplastic, but sometimes also referring to connective tissue disease. Post the Definition of disseminated to Facebook, Share the Definition of disseminated on Twitter, … overt disease sets in, first as chronic infections of the skin and mucous membranes and then as. It can also spread and cause disease throughout your body. Disseminated disease is most often seen in immunocompromised patients. If it does cause symptoms, the most common are mild to moderate pain and stiffness in your upper back. Our Word of the Year 'pandemic,' plus 11 more. People with herpes zoster most commonly have a rash in one or two adjacent dermatomes (localized zoster). You cut your finger or nick your leg and your body gets to work to stop the bleeding. The term may sometimes also characterize connective tissue disease . It may be a secondary complication of any of numerous obstetrical, surgical, infectious, hemolytic, and neoplastic disorders, all of which activate in some way the intrinsic coagulation ⦠: widely dispersed in a tissue, organ, or the entire body disseminated gonococcal disease ⦠overt disease sets in, first as chronic infections of the skin and mucous membranes and then as disseminated, systemic infections. It damages the ⦠Herpes zoster is the reactivation of the virus and its spread from a single dorsal root or cranial nerve ganglion to the corresponding dermatome and ⦠Incidence rates have ranged from 0.06 to 1.56 cases per million vaccinated, and mortality rates have remained at â60% (1â7).Of 946 patients with primary immunodeficiency, including 29 with severe combined immunodeficiencies, diagnosed from 1980 ⦠Please tell us where you read or heard it (including the quote, if possible). Accessed 30 Nov. 2020. Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. Disseminated disease refers to a diffuse disease-process, generally either infectious or neoplastic. A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to "seed" other areas of the body. Test Your Knowledge - and learn some interesting things along the way. As well as causing the brain and spinal cord to become inflamed, ADEM also attacks the nerves of the central nervous system and damages their myelin insulation, which, as a result, destroys the white matter. Mycobacterium avium complex (MAC) is widely distributed in the environment, and exposure to the organisms is common. It can infect one part of your body, like your lungs, bones, or intestines. The subcommittee on DIC of the International Society on Thrombosis and Haemostasis has suggested the following definition for DIC: An acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes.